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Genetic Epidemiology of COPD

Short Name
COPD
Institution(s)
Brigham & Women's Hospital
Type of Omics
WGS
RNASeq
Methylomics
Approx. Sample Size 100WGS EOCOPD (ph1), 1885WGS COPDGene (ph1), 7400WGS (ph2), 1000WGS COPDGene (ph3), 800RNASeq COPDGene (ph4), 11,500Methyl COPDGene (ph5)
Disease/Phenotype
Genetic risk and protective variants in COPD in African American and European American populations
Starting Phase
Phase 1
dbGaP ID
phs000951
phs000946
TOPMed Accession #
Please see this TOPMed Project's Parent Studies.
Omics Center(s) Phase 1
Northwest Genomics Center
Omics Center(s) Phase 2
Broad Institute Genomics Platform
Omics Center(s) Phase 3
Broad Institute Genomics Platform
Omics Center(s) Phase 4
Northwest Genomics Center
Omics Center(s) Phase 5
Northwest Genomics Center
Phases Involved
1
2
3
4
5
Other Funding
Populations
African American (30%)
PI

Ed Silverman
Contact

Ed Silverman
NIH Program Officer
Weiniu Gan
Phenotype Liaison
Michael Cho
Carla Wilson
Steering Committee Representatives
Terri Beaty
Ed Silverman
P&P primary
John Hokanson
P&P alternate
Terri Beaty
Project
COPD
WGS Released
10825
WGS Subjects
10677
Methylation Released
12215
Methylation Subjects
7357
RNA-seq Released
723
RNA-seq Subjects
386
Metabolomics Released
9141
Metabolomics Subjects
6607
Released
Yes