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Publications

Submitting Author Title Journal Name Publication Date PMID Associated Proposal ID(s)
Tamar Sofer Polygenic scores for obstructive sleep apnoea reveal pathways contributing to cardiovascular disease EBioMedicine 40472801 17176
Huan, Tianxiao Epigenome-wide DNA methylation association study of CHIP provides insight into perturbed gene regulation Nature Communications 40393957 16033
de Vries, Paul Genetic study of von Willebrand factor antigen levels ≤ 50 IU/dL identifies variants associated with increased risk of VWD and bleeding J Thromb Haemost 40368142 14762
Sanghun Lee Associations of APOE Variants with Sphingomyelin and Cholesterol Metabolites across the Life-course in Diverse Populations Metabolomics 40335834 17774
Hong, Yun Soo Deleterious mitochondrial heteroplasmies exhibit increased longitudinal change in variant allele fraction iScience 40487423 17538
Karasik, David Multi-ancestry whole genome sequencing analysis of lean body mass Genome Biology 40296127 5676
Sanghun Lee On the analysis of metabolite quantitative trait loci: Impact of different data transformations and study designs Science Advances 40215300 17009
Justice, Anne Whole genome sequencing analysis of body mass index identifies novel African ancestry-specific risk allele Nature Communications 40216759 982
Dinardo, Carla Clinics and genetics of hyperhemolysis syndrome in patients with sickle cell disease Transfusion 40172242 4500
Xu, Weiling Mitochondrial DNA Copy Number Variation in Asthma Risk, Severity, and Exacerbations J Allergy Clin Immunol. 39237012 4252
de Vries, Paul Rare damaging CCR2 variants are associated with lower lifetime cardiovascular risk Genome Medicine 40119478 14255
Choi, Seung Hoan Sequencing in over 50,000 cases identifies coding and structural variation underlying atrial fibrillation risk Nature Genetics 40050430 2254
Li, Xihao A statistical framework for powerful multi-trait rare variant analysis in large-scale whole-genome sequencing studies Nature Computational Science 39920506 10000
Peterson, Tess Proteomic Signature of HIV-Associated Subclinical Left Atrial Remodeling and Incident Heart Failure Nat Commun. 39800750 17166
Auer, Paul Genomic and phenotypic correlates of mosaic loss of chromosome Y in blood Am J Hum Genet. 39809269 16075
Little, Amarise General Kernel Machine Methods for Multi-Omics Integration and Genome-Wide Association Testing With Related Individuals Genetic Epidemiology 39812506 16537
Su, Jessica Lasky miRNAome-Metabolome Wide Association Study Reveals Effects of miRNA Regulation in Eosinophilia and Airflow Obstruction in Childhood Asthma EBioMedicine 39740296 17768
Ryu, Min Hyung Computational Deconvolution of Cell Type-Specific Gene Expression in COPD and IPF Lungs Reveals Disease Severity Associations BMC Genomics 39695952 18261
Wu, Lang Identification of proteins associated with type 2 diabetes risk in diverse racial and ethnic populations Diabetologia 39349773 13066
Borda, Victor Genetics of Latin American Diversity (GLAD) Project: insights into population genetics and association studies in recently admixed groups in the Americas Cell Genomics 39486408 9463
Yaser, Mohammad Machine learning-based clustering identifies obesity subgroups with differential multi-omics profiles and metabolic patterns Obesity 39497627 17802
Arora, Pankaj Cardiovascular Risk Factors and Genetic Risk in Transthyretin V142I Carriers JACC Heart Failure 39520444 14719
Kim, John Genomic and Serological Rheumatoid Arthritis Biomarkers, MUC5B Promoter Variant, and Interstitial Lung Abnormalities Annals of the American Thoracic Society 39405163 13519
Do, Ron Rare variant contribution to the heritability of coronary artery disease Nature Communications 39384761 13951
Taylor, Kent Metagenomic Study of the MESA: Detection of Gemella Morbillorum and Association With Coronary Heart Disease J Am Heart Assoc. 39344648 17063
Dinardo, Carla Genetic variants associated with white blood cell count amongst individuals with sickle cell disease British Journal of Hematology 39279196 6176
Liu, Chunyu Association analysis of mitochondrial DNA heteroplasmic variants: Methods and application Mitochondrion 39245194 12691
Huffman, Jennifer Whole-genome analysis of plasma fibrinogen reveals population-differentiated genetic regulators with putative liver roles Blood 39226462 10430
Sun, Quan A genome-wide association study of alloimmunization in the TOPMed OMG-SCD cohort identifies a locus on chromosome 12 Transfusion 38966903 15041
Raffield, Laura Whole Genome Sequencing Based Analysis of Inflammation Biomarkers in the Trans-Omics for Precision Medicine (TOPMed) Consortium Human Molecular Genetics 38747556 16345
Su, Jessica Lasky Metabolite signatures associated with microRNA miR-143-3p serve as drivers of poor lung function trajectories in childhood asthma eBioMedicine 38458111 10705
Wheeler, Heather Transcriptome-wide association study of the plasma proteome reveals cis and trans regulatory mechanisms underlying complex traits AJHG 38320554 13310
de Vries, Paul A genetic association study of circulating coagulation Factor VIII and von Willebrand Factor levels Blood 38320121 3158
Kasela, Silva Interaction molecular QTL mapping discovers cellular and environmental modifiers of genetic regulatory effects American Journal of Human Genetics 38181730 5508
Yun, Jeong Clonal Somatic Mutations in Chronic Lung Diseases Are Associated with Reduced Lung Function Am J Respir Crit Care Med. 37788444 13056
Franceschini, Nora Genome-wide study investigating effector genes and polygenic prediction for kidney function in persons with ancestry from Africa and the Americas Cell Genomics 38190104 16086
Armstrong, Nicole Whole Genome Sequence Analysis of Apparent Treatment Resistant Hypertension Status in Participants from the Trans-Omics for Precision Medicine Program Frontiers in Genetics- Special Issue on "Linking Genetic Variation to Drug Response: Discovery and Challenges" 38162683 2577
Wang, Yuxuan Rare variants in long non-coding RNAs are associated with blood lipid levels in the TOPMed Whole Genome Sequencing Study American Journal of Human Genetics 37802043 13704
Hu, Xiaowei Multi-ancestry epigenome-wide analyses identify methylated sites associated with aortic augmentation index in TOPMed MESA Scientific Reports 37848499 12665
Hasbani, Natalie Type 2 Diabetes Modifies the Association of CAD Genomic Risk Variants With Subclinical Atherosclerosis Circulation: Genomic and Precision Medicine 38014529 9771
Pino-Yanes, Maria Epigenomic Response to Albuterol Treatment in Asthma-Relevant Airway Epithelial Cells Clinical Epigenetics 37784136 15876
Wheeler, Heather Multivariate adaptive shrinkage improves cross-population transcriptome prediction and association studies in underrepresented populations HGG Advances 37869564 13309
Tobias, Deirdre Clonal Hematopoiesis of Indeterminate Potential (CHIP) and Incident Type 2 Diabetes Risk Diabetes Care 37756531 5687
Lappalainen, Tuuli Genetic control of mRNA splicing as a potential mechanism for incomplete penetrance of rare coding variants Genetics 37348055 14988
Raffield, Laura Canonical correlation analysis for multi-omics: Application to cross-cohort analysis PLOS Genetics 37216410 10110
Kachroo, Priyadarshini Epigenome-wide DNA methylation association study of circulating IgE levels identifies novel targets for asthma EBioMedicine 37598461 12306
Auer, Paul Mosaic chromosomal alterations in blood across ancestries using whole-genome sequencing Nature Genetics 37904051 13748
Liu, Chunyu Association Between Whole Blood-Derived Mitochondrial DNA Copy Number, Low-Density Lipoprotein Cholesterol, and Cardiovascular Disease Risk Journal of the American Heart Association 37804200 3129
Pino-Yanes, Maria Novel insights into the whole blood DNA methylome of asthma in ethnically diverse children and youth European Respiratory Journal 37802634 14752
Tahir, Usman Protein-Metabolite Association Studies Identify Novel Proteomic Determinants of Metabolite Levels in Human Plasma Cell Metabolism 37582364 11386
248 Publications
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