African American Coronary Artery Calcification project
|
AA_CAC |
Kent D. Taylor Jerome Rotter |
1409 |
African American families |
2 |
WGS |
Identification of Common Genetic Variants for Atrial Fibrillation and PR Interval - Atrial Fibrillation Genetics Consortium
|
AFGen |
Patrick Ellinor |
2799 |
AF cases all EA |
1, Other Funding |
WGS |
Atrial Fibrillation Biobank Ludwig Maximilian University Study
|
AFLMU |
Mortiz Sinner |
248 co-funded, 102 phase 2.5 |
AF onset at ≤65years, or presentation for catheter ablation of AF |
Other Funding |
WGS |
Integrative Genomic Studies of Heart and Blood Related Traits in Africans
|
Africa6K |
Sarah Tishkoff Scott Williams |
|
Most Ancestries in Africa (7500 Samples) |
4, 8 |
WGS, RNASeq |
Integrative Genomic Studies of Heart and Blood Related Traits in Africans
|
Africa6K |
Sarah Tishkoff Scott Williams |
7500DNA |
Most Ancestries in Africa (7500 Samples) |
4 |
WGS |
Genetics of Cardiometabolic Health in the Amish
|
Amish |
Braxton D. Mitchell |
1100 |
Old Order Amish large extended pedigrees |
1 |
WGS |
Genetics of Cardiometabolic Health in the Amish
|
Amish |
Braxton D. Mitchell |
1100 |
Old Order Amish large extended pedigrees |
1 |
WGS |
Atherosclerosis Risk in Communities Study VTE cohort
|
ARIC |
Eric Boerwinkle |
3937 |
adults (aged 45-65 at baseline) who lived in four U.S. communities across the country |
2, 6, 8 |
WGS, RNASeq, Methylomics |
Asthma Translational Genomics Collaborative
|
ATGC |
Esteban Burchard L. Keoki Williams Hakon Hakonarson |
15580 WGS ph3, 3500 RNAseq ph4 |
African American, Mexican, and Puerto Rican Individuals |
3, 4, 8 |
WGS, RNASeq |
Molecular Mechanisms of Inherited Cardiomyopathies and Arrhythmias in the Australian Familial AF Study
|
AustralianFamilialAF |
Diane Fatkin |
120 |
European Ancestry cases with early-onset AF |
1 |
WGS |
New Approaches for Empowering Studies of Asthma in Populations of African Descent - Barbados Asthma Genetics Study
|
BAGS |
Kathleen Barnes |
1100 |
Barbados families of African descent with >40% of asthmatic members |
1 |
WGS |
Barbados Asthma Genetics Study
|
BAGS |
Kathleen Barnes |
1100 |
Barbados families of African descent with >40% of asthmatic members |
1 |
WGS |
The Boston-Colombia Collaborative for Adverse Pregnancy Outcomes
|
BCC-PREG |
Kathryn J. Gray Richa Saxena |
|
White, Black, Asian, Hispanic, White Hispanic, AfroCaribbean, American Indians, Mixed |
7 |
WGS |
Mount Sinai BioMe Biobank
|
BioMe |
Ruth J.F. Loos Eimear Kenny |
8769 CAD, 2644 COPD |
African American (24%), Hispanic/Latino (35%), European (32%), Other (10%) |
3 |
WGS |
Mount Sinai BioMe Biobank
|
BioMe |
Ruth J.F. Loos Eimear Kenny |
8769 cad, 2644 copd |
African American (24%), Hispanic/Latino (35%), European (32%), Other (10%) |
3 |
WGS |
The Vanderbilt University BioVU Atrial Fibrillation Genetics Study
|
BioVU_AF |
M. Benjamin Shoemaker Dan Roden |
|
Patients with AF referred for AF ablation |
Other Funding |
WGS |
Boston-Brazil Collaborative Study of Sickle Cell Disease
|
Boston-Brazil_SCD |
Vijay G. Sankaran |
958 |
Brazilian |
2 |
WGS |
Boston-Brazil Collaborative Study of Sickle Cell Disease
|
Boston-Brazil_SCD |
Vijay G. Sankaran |
958 |
patients with SCD from Brazil |
2, 5 |
WGS |
Childhood Asthma Management Program
|
CAMP |
Scott Weiss |
???wgs (ph3), 1700metab (ph5), 1700methyl (ph5) |
children (ages 5-12 at time of screening) with chronic asthma |
3, 5 |
WGS, Metabolomics, Methylomics |
Whole Genome Sequence Analysis in Early Cerebral Small Vessel Disease
|
CARDIA |
Myriam Fornage Lifang Hou |
3622WGS (ph3), 9480Methyl (ph5) |
African American and White Young Adults |
3, 5, 8 |
WGS, Proteomics, Methylomics |
Coronary Artery Risk Development in Young Adults
|
CARDIA |
Myriam Fornage Lifang Hou |
3622wgs (ph3), 9480methyl (ph5) |
African American and White Young Adults |
3, 5, 8 |
WGS, RNASeq, Metabolomics, Proteomics, Methylomics |
Childhood Asthma Research and Education Network: Best Add-on Therapy Giving Effective Responses
|
CARE_BADGER |
Fernando Martinez |
|
Children with mild-to-moderate uncontrolled asthma |
3 |
WGS |
Childhood Asthma Research and Education Network: Characterizing the Response to a Leuikotriene Receptor Agonis and an Inhaled Corticosteroid
|
CARE_CLIC |
Fernando Martinez |
219 |
Children ages 6-17 with mild-to-moderate asthma |
3 |
WGS |
Childhood Asthma Research and Education Network: Pediatric Asthma Controller Trial
|
CARE_PACT |
Fernando Martinez |
|
children aged 6-14 with mild-moderate persistent asthma |
3 |
WGS |
Childhood Asthma Research and Education Network: Treating Children to Prevent Exacerbations of Asthma
|
CARE_TREXA |
Fernando Martinez |
|
Children with mild persistent asthma under good control with low dose ICS |
3 |
WGS |
The Duke CATHeterization GENetics Study
|
CATHGEN |
William Kraus Albert Sun |
|
CATHGEN participants (age ≥18 undergoing cardiac catheterization for ischemic heart disease) with AF |
Other Funding |
WGS |
Cleveland Clinic Atrial Fibrillation Study
|
CCAF |
Mina Chung John Barnard |
365 |
age ≥18 with a history of recurring or persistent lone atrial fibrillation |
1 |
WGS |
Cleveland Family Study - WGS Collaboration
|
CFS |
Susan Redline |
1000 |
African American |
1 |
WGS |
Cleveland Family Study
|
CFS |
Susan Redline |
1000 |
African American |
1 |
WGS |
Children's Health Study: Integrative Genetic Approaches to Gene-Air Pollution Interactions in Asthma
|
ChildrensHS_GAP |
Frank Gilliland |
|
young adults (over 18 years old) who live in Southern California |
3 |
WGS |
Children's Health Study: Integrative Genomics and Environmental Research of Asthma
|
ChildrensHS_IGERA |
Frank Gilliland |
231 |
children (Hispanic-White) in southern California |
3 |
WGS |
Children's Health Study: Effects of Air Pollution on the Development of Obesity in Children
|
ChildrensHS_MetaAir |
Frank Gilliland |
|
overweight or obese children in southern California |
3 |
WGS |
Genetics Sub-Study of Chicago Initiative to Raise Asthma Health Equity
|
CHIRAH |
Rajesh Kumar |
318 |
participants ages 8-14 or 18-40 with asthma living in Chicago |
3 |
WGS |
Cardiovascular Health Study
|
CHS |
Bruce Psaty Russell Tracy |
3600 |
Adults From the USA Aged 65 and Older |
3 |
WGS |
Cardiovascular Health Study
|
CHS |
Bruce Psaty Russell Tracy |
3600 |
Adults From the USA Aged 65 and Older |
3 |
WGS |
Cardiovascular Health Study
|
CHS VTE |
Susan Heckbert |
71 |
adults ≥65 from the USA; adjudicated idiopathic VTE, MI, stroke, or CHD during follow-up |
2 |
WGS |
Genetic Epidemiology of COPD
|
COPD |
Ed Silverman |
100WGS EOCOPD (ph1), 1885WGS COPDGene (ph1), 7400WGS (ph2), 1000WGS COPDGene (ph3), 800RNASeq COPDGene (ph4), 11,500Methyl COPDGene (ph5) |
>10,000 non-Hispanic white and African-American, nearly all current and former smokers with and without COPD |
1, 2, 3, 4, 5, Other Funding |
WGS, RNASeq, Methylomics |
Genetic Epidemiology of COPD Study
|
COPDGene |
Ed Silverman |
1885 (ph1), 7400 (ph2), 1000 (ph3), 800rna (ph4), 11,500methyl (ph5) |
African American, non-Hispanic White |
1, 2, 3, 4, 5, Other Funding |
WGS, RNASeq, Methylomics |
Genetic Epidemiology of COPD Study
|
COPDGene COPDMet |
Ed Silverman |
|
Current, Former, and Never Smokers (ages 45-80) |
7 |
Metabolomics |
Plasma and BALF Metabolomics in COPDGene and SPIROMICS
|
COPDMet |
Russell Bowler |
|
Current, Former, and Never Smokers |
7 |
Metabolomics |
The Genetic Epidemiology of Asthma in Costa Rica - Asthma in Costa Rica cohort
|
CRA |
Scott Weiss |
1300wgs (ph1), 1300metab (ph5), 1300methyl (ph5) |
Costa Rica is a Special Hispanic population with asthma prevalence at 24% |
1, 3, 5 |
WGS, Metabolomics, Methylomics |
The Genetic Epidemiology of Asthma in Costa Rica and the Childhood Asthma Management Program
|
CRA_CAMP |
Scott Weiss |
1300WGS (ph1), 5319WGS (ph3), 3000Metab (ph5), 3000Methyl (ph5) |
Costa Rica is a Special Hispanic Population with Asthma Prevalence at 24% |
1, 3, 5 |
WGS, Metabolomics, Methylomics |
Determining the association of chromosomal variants with non-PV triggers and ablation-outcome in DECAF
|
DECAF |
Sanghamitra Mohanty |
|
adults (>18 years) with AF |
1 |
WGS |
Diabetes Heart Study
|
DHS |
Nicholette Palmer Donald W. Bowden |
|
European American and African American participants from families with multiple cases of T2D |
2 |
WGS |
Down Syndrome Associated Atrioventricular Septal Defects: New Omic Resources
|
DS_CHD |
Stephanie L. Sherman |
471WGS (ph5.5) |
Parent-Offspring Trios |
Other Funding |
WGS |
Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints
|
ECLIPSE |
Ed Silverman |
2400 (ph3) |
Adults Aged 40-75 with at least 10 Pack-years of Smoking |
3 |
WGS |
Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-points
|
ECLIPSE |
Ed Silverman |
2400 (ph3) |
Adults Aged 40-75 with at least 10 Pack-years of Smoking |
3 |
WGS |
Estonian Genome Center
|
EGCUT |
Tonu Esko |
2900wgs |
adults (age ≥18) from Estonia |
Other Funding |
WGS |
Boston Early-Onset COPD Study
|
EOCOPD |
Ed Silverman |
100 |
early onset (< 53 years) COPD without alpha-1 antitrypsin deficiency and extended pedigrees |
1 |
WGS |
Framingham Heart Study
|
FHS |
Joanne Murabito Nancy Heard-Costa Dan Levy George O'Connor |
4089wgs (ph1), 1861rnaseq (ph5), 3400metab (ph5), 1900methyl (ph5) |
Three generation European ancestry pedigrees |
1, 5, Other Funding |
WGS, RNASeq, Metabolomics, Proteomics, Methylomics |