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Whole Genome Sequencing Identifies CRISPLD2 as a Lung Function Gene in Children with Airway Hyperresponsive Asthma

Manuscript ID: 5753

Submitting Author
Weiss, Scott
Submitting Author's Email
scott.weiss@channing.harvard.edu
Authors
Priyadarshini Kachroo1 *, Julian Hecker1, 2 *, Bo Chawes3 *, Tarunveer S. Ahluwalia3,
Michael Cho1, Dandi Qiao1, Rachel S. Kelly1, Su H. Chu1, Yamini V. Virkud1,4, Mengna Huang1, Kathleen C. Barnes5, Esteban G. Burchard6, Celeste Eng6, Donglei Hu6, Juan C. Celedon7, Michelle Daya5, Albert M. Levin8,9, Hongsheng Gui10,11, Keoki Williams10,11, Erick Forno7, Angel C.Y. Mak6, Lydiana Avila12, Klaus Bønnelykke3, Hans Bisgaard3, Christoph Lange2, Scott T.Weiss1, Jessica Lasky-Su1, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium.
Journal name for most current submission
Chest
Associated TOPMed paper proposal
A family based analysis of coding and regulatory variants for asthma
This manuscript has been approved by the original paper proposal's Working Group(s) or is "single PI" *
This manuscript has been approved by the original paper proposal's Working Group(s) or is "single PI"
Acknowledgments
I have followed instructions for TOPMed Acknowledgments
I've received approval for all data sets used in this manuscript, including adding new data sets and canceling all unused ones. *
I've received approval for all data sets used in this manuscript, including adding new data sets and canceling all unused ones.
I have followed the Data Use Limitations for each of the data sets used in this manuscript, if applicable. *
Yes
I've included at least 1 co-author from each study used in analysis or the PI declined an offer to have their study represented. *
Yes
I certify that all co-authors have reviewed and approved the manuscript for submission. *
Yes
I've included at least 1 DCC/ACC author, or they declined authorship or deemed acknowledgement sufficient.
I have not
I’ve included at least 1 IRC author, or they declined authorship or deemed acknowledgement sufficient.
I have not
I've included at least 1 author from relevant omics center(s) or they declined authorship or deemed acknowledgement sufficient.
I have not

TOPMed data used in this manuscript

The data set approvals listed here should match the TOPMed data used in this manuscript.

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Parent Study: Consent Group Review Status Actions
CRA:DS-ASTHMA-IRB-MDS-RD Approved
GALAII:DS-LD-IRB-COL Approved
SAGE:DS-LD-IRB-COL Approved