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Whole genome sequence analyses of eGFR in 23,732 people representing multiple ancestries in the NHLBI trans-omics for precision medicine (TOPMed) consortium

Submitting Author
Franceschini, Nora
Submitting Author's Email
Authors
Lin BM1*, Grinde KE2*, Brody JA3, Raffield LM4, Mychaleckyj JC5, Thornton TA6, Perry JA7, Baier LJ8, de las Fuentes L9, Guo X10, Heavner BD6, Hanson RL8, Hung Y11, Hsiung AC12, Hwang S13,14, Irvin MR15, Jain D6, Kelly TN16, Kobes S8, Lange L17, Lash JP18, Li Y1,4, Liu X19, Musani SK20, Papanicolaou GJ21, Parsa A22, Reiner AP23, Salimi S24, Sheu WH25, Shuldiner AR7, Smith AV26, Smith JA27, Tin A28, Vaidya D29, Wallance RB30, Yanek LR29, Young BA31, Zhao W27, Abecasis G32,33, Arnett DK34, Boerwinkle E35,36, Cai J1, Chen YI37, Cooperberg C23, Correa A20, Cupples LA38, He J16, Kardia SLR27, Mathias RA29, Mitchell BD7,39, Nickerson DA40, Turner ST41, Ramachandran VS42, Rotter JI, Levy D13,14, Kramer HJ43,44, Köttgen A28,45, Rich SS5, Lin D1, Browning SR6, Franceschini N46, on behalf of the TOPMed Kidney Working Group
Journal name for most current submission
EBioMedicine
Associated TOPMed paper proposal
This manuscript has been approved by the original paper proposal's Working Group(s) or is "single PI"
This manuscript has been approved by the original paper proposal's Working Group(s) or is "single PI"
Acknowledgments
I have followed instructions for TOPMed Acknowledgments
I've received approval for all data sets used in this manuscript, including adding new data sets and canceling all unused ones.
I've received approval for all data sets used in this manuscript, including adding new data sets and canceling all unused ones.
I have followed the Data Use Limitations for each of the data sets used in this manuscript, if applicable.
Yes
I've included at least 1 co-author from each study used in analysis or the PI declined an offer to have their study represented.
Yes
I certify that all co-authors have reviewed and approved the manuscript for submission.
Yes
Upload all necessary study-specific approval documentation.
I've included at least 1 DCC/ACC author, or they declined authorship or deemed acknowledgement sufficient.
I've included at least 1 DCC/ACC author, or they declined authorship or deemed acknowledgement sufficient.
I’ve included at least 1 IRC author, or they declined authorship or deemed acknowledgement sufficient.
I’ve included at least 1 IRC author, or they declined authorship or deemed acknowledgement sufficient.
I've included at least 1 author from relevant omics center(s) or they declined authorship or deemed acknowledgement sufficient.
I've included at least 1 author from relevant omics center(s) or they declined authorship or deemed acknowledgement sufficient.

TOPMed data used in this manuscript

The data set approvals listed here should match the TOPMed data used in this manuscript.

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Please "cancel" any data set requests that were not used in this manuscript. Note: only the paper proposal submitter or their designated updater can cancel data sets.

Parent Study: Consent Group Review Status
ARIC:DS-CVD-IRB Approved automatically after 2 weeks
ARIC:DS-CVD-IRB Approved automatically after 2 weeks
ARIC:HMB-IRB Approved automatically after 2 weeks
ARIC:HMB-IRB Approved automatically after 2 weeks
Amish:HMB-IRB-MDS Approved automatically after 2 weeks
CHS:DS-CVD-MDS Approved
CHS:DS-CVD-MDS Approved
CHS:DS-CVD-NPU-MDS Approved
CHS:DS-CVD-NPU-MDS Approved
CHS:HMB-MDS Approved
CHS:HMB-MDS Approved
CHS:HMB-NPU-MDS Approved
CHS:HMB-NPU-MDS Approved
FHS:HMB-IRB-MDS Approved automatically after 2 weeks
FHS:HMB-IRB-NPU-MDS Approved automatically after 2 weeks
GENOA:DS-ASC-RF-NPU Approved
GENOA:DS-ASC-RF-NPU Approved
GenSalt:GRU-IRB Approved
GeneSTAR:DS-CVD-IRB-NPU-MDS Approved
GeneSTAR:DS-CVD-IRB-NPU-MDS Approved
HyperGEN:DS-CVD-IRB-RD Approved
HyperGEN:DS-CVD-IRB-RD Approved
HyperGEN:GRU-IRB Approved
HyperGEN:GRU-IRB Approved
JHS:DS-FDO-IRB Approved
JHS:DS-FDO-IRB Approved
JHS:DS-FDO-IRB-NPU Approved
JHS:DS-FDO-IRB-NPU Approved
JHS:HMB-IRB Approved
JHS:HMB-IRB Approved
JHS:HMB-IRB-NPU Approved
JHS:HMB-IRB-NPU Approved
MESA:HMB Approved
MESA:HMB Approved
MESA:HMB-NPU Approved
MESA:HMB-NPU Approved
THRV:DS-CVD-IRB-COL-NPU-RD Approved automatically after 2 weeks
WHI:HMB-IRB Approved
WHI:HMB-IRB Approved
WHI:HMB-IRB-NPU Approved
WHI:HMB-IRB-NPU Approved
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