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Type 2 Diabetes Modifies the Association of CAD Genomic Risk Variants With Subclinical Atherosclerosis

Manuscript ID: 16294

Submitting Author
Hasbani, Natalie
Submitting Author's Email
Authors
Natalie R. Hasbani MPH1, Kenneth E. Westerman PhD2,3,4, Soo Heon Kwak MD5, Han Chen PhD1,6, Xihao Li PhD7, Daniel Dicorpo MS8, Jennifer Wessel PhD9, Joshua C. Bis PhD10, Chloè Sarnowski PhD1, Peitao Wu PhD11, Lawrence F. Bielak DDS12, Xiuqing Guo PhD13, Nancy Heard-Costa PhD14, Gregory Kinney PhD15, Michael C Mahaney PhD16, May E. Montasser PhD17, Nicholette D. Palmer PhD18, Laura M. Raffield PhD19, James G. Terry MS20, Lisa R. Yanek MPH21, Jessica Bon MD22, Donald W. Bowden PhD18, Jennifer A. Brody BA10, Ravindranath Duggirala PhD23, David R. Jacobs PhD24, Rita R. Kalyani MD21, Leslie A. Lange PhD25, Braxton D. Mitchell PhD17,26, Jennifer A. Smith PhD12,27, Kent D. Taylor PhD13, April Carson PhD28, Joanne E Curran PhD16, Myriam Fornage PhD29, Barry I. Freedman MD30, Stacey Gabriel PhD31, Richard A Gibbs PhD32, Namrata Gupta PhD31, Sharon L.R. Kardia PhD12, Brian G. Kral MD21, Zeineen Momin MS32, Anne B. Newman MD33, Wendy S. Post MD34, Karine A. Viaud-Martinez35, Kendra A. Young PhD15, Lewis C. Becker MD21, Alain Bertoni MD, MPH36, John Blangero PhD16, John J. Carr MD20, Katherine Pratte, PhD37, Bruce M. Psaty MD, PhD38,39,40, Stephen S. Rich PhD41, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed Atherosclerosis Working Group, TOPMed Diabetes Working Group, Joesph C. Wu MD, PhD42,43,44, Rajeev Malhotra MD45, Patricia A. Peyser PhD12, Alanna C Morrison PhD1, Ramachandran S. Vasan MD46,47, Xihong Lin PhD7, Jerome I. Rotter MD48, James B. Meigs MD49,4,50, Alisa K. Manning PhD2,3,4, Paul S. de Vries PhD1
Journal name for most current submission
Circulation: Genomic and Precision Medicine
Associated TOPMed paper proposal
This manuscript has been approved by the original paper proposal's Working Group(s) or is "single PI" *
This manuscript has been approved by the original paper proposal's Working Group(s) or is "single PI"
Acknowledgments
I have followed instructions for TOPMed Acknowledgments
I've received approval for all data sets used in this manuscript, including adding new data sets and canceling all unused ones. *
I've received approval for all data sets used in this manuscript, including adding new data sets and canceling all unused ones.
I have followed the Data Use Limitations for each of the data sets used in this manuscript, if applicable. *
Yes
I've included at least 1 co-author from each study used in analysis or the PI declined an offer to have their study represented. *
Yes
I certify that all co-authors have reviewed and approved the manuscript for submission. *
Yes
I've included at least 1 DCC/ACC author, or they declined authorship or deemed acknowledgement sufficient.
I've included at least 1 DCC/ACC author, or they declined authorship or deemed acknowledgement sufficient.
I’ve included at least 1 IRC author, or they declined authorship or deemed acknowledgement sufficient.
I’ve included at least 1 IRC author, or they declined authorship or deemed acknowledgement sufficient.
I've included at least 1 author from relevant omics center(s) or they declined authorship or deemed acknowledgement sufficient.
I've included at least 1 author from relevant omics center(s) or they declined authorship or deemed acknowledgement sufficient.

TOPMed data used in this manuscript

The data set approvals listed here should match the TOPMed data used in this manuscript.

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Parent Study: Consent Group Review Status Actions
ARIC:DS-CVD-IRB Approved
ARIC:HMB-IRB Approved
Amish:HMB-IRB-MDS Approved automatically after 2 weeks
CARDIA:HMB-IRB Approved automatically after 2 weeks
CARDIA:HMB-IRB-NPU Approved automatically after 2 weeks
CHS:DS-CVD-MDS Approved
CHS:DS-CVD-NPU-MDS Approved
CHS:HMB-MDS Approved
CHS:HMB-NPU-MDS Approved
COPDGene:DS-CS-RD Approved
COPDGene:HMB Approved
DHS:DS-DHD-IRB-COL-NPU Approved
DHS:HMB-IRB-COL-NPU Approved
FHS:HMB-IRB-MDS Approved automatically after 2 weeks
FHS:HMB-IRB-NPU-MDS Approved automatically after 2 weeks
GENOA:DS-ASC-RF-NPU Approved
GeneSTAR:DS-CVD-IRB-NPU-MDS Approved automatically after 2 weeks
JHS:DS-FDO-IRB Approved
JHS:DS-FDO-IRB-NPU Approved
JHS:HMB-IRB Approved
JHS:HMB-IRB-NPU Approved
MESA:HMB Approved
MESA:HMB-NPU Approved
SAFS:DS-DHD-IRB-PUB-MDS-RD Approved
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