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Mitochondrial DNA copy number can influence mortality and cardiovascular disease via methylation of nuclear DNA CpGs

Manuscript ID: 10144

Submitting Author
Liu, Chunyu
Submitting Author's Email
Authors
Christina A. Castellani, Ryan J. Longchamps, Jason A. Sumpter, Charles E. Newcomb, John A. Lane, Megan L. Grove, Jan Bressler, Jennifer A. Brody, James S. Floyd, Traci M. Bartz, Kent D. Taylor, Penglong Wang, Adrienne Tin, Josef Coresh, James S. Pankow, Myriam Fornage, Eliseo Guallar, Brian O’Rourke, Nathan Pankratz, Chunyu Liu, Daniel Levy, Nona Sotoodehnia, Eric Boerwinkle, Dan E. Arking
Journal name for most current submission
Genome Medicine
Associated TOPMed paper proposal
This manuscript has been approved by the original paper proposal's Working Group(s) or is "single PI"
This manuscript has been approved by the original paper proposal's Working Group(s) or is "single PI"
Acknowledgments
I have followed instructions for TOPMed Acknowledgments
I've received approval for all data sets used in this manuscript, including adding new data sets and canceling all unused ones.
I've received approval for all data sets used in this manuscript, including adding new data sets and canceling all unused ones.
I have followed the Data Use Limitations for each of the data sets used in this manuscript, if applicable.
Yes
I've included at least 1 co-author from each study used in analysis or the PI declined an offer to have their study represented.
Yes
I certify that all co-authors have reviewed and approved the manuscript for submission.
Yes
I've included at least 1 DCC/ACC author, or they declined authorship or deemed acknowledgement sufficient.
I have not
I’ve included at least 1 IRC author, or they declined authorship or deemed acknowledgement sufficient.
I have not
I've included at least 1 author from relevant omics center(s) or they declined authorship or deemed acknowledgement sufficient.
I have not

TOPMed data used in this manuscript

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Parent Study: Consent Group Review Status
ARIC:DS-CVD-IRB Approved automatically after 2 weeks
ARIC:HMB-IRB Approved automatically after 2 weeks
CARDIA:HMB-IRB Approved
CARDIA:HMB-IRB-NPU Approved
FHS:HMB-IRB-MDS Approved
FHS:HMB-IRB-NPU-MDS Approved
GENOA:DS-ASC-RF-NPU Approved
JHS:DS-FDO-IRB Approved
JHS:DS-FDO-IRB-NPU Approved
JHS:HMB-IRB Approved
JHS:HMB-IRB-NPU Approved
MESA:HMB Approved
MESA:HMB-NPU Approved
WHI:HMB-IRB Approved
WHI:HMB-IRB-NPU Approved
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