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Genetic diversity fuels gene discovery for tobacco and alcohol use

Manuscript ID: 13650

Submitting Author
Saunders, Gretchen
Submitting Author's Email
Authors
Gretchen R.B. Saunders
Xingyan Wang
Fang Chen
Seon-Kyeong Jang
Mengzhen Liu
Chen Wang
Shuang Gao
Yu Jiang
Chachrit Khunsriraksakul
Jacqueline M. Otto
NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium
Masato Akiyama
Alvaro Alonso
R. Graham Barr
Traci M. Bartz
Diane M. Becker
Emelia J. Benamin
Joshua C. Bis
John Blangero
Jason D. Boardman
Dorret I. Boomsma
Donald W. Bowden
Jennifer A. Brody
Yii-Der Ida Chen
Michael H. Cho
Hélène Choquet
John W. Cole
Joanne E. Curran
Ravindranath Duggirala
Charles B. Eaton
Tõnu Esko
Barry I. Freeedman
Sina A. Gharib
Christian Gieger
David C. Glahn
Scott D. Gordon
Charles C. Gu
Xiuqing Guo
Jeffrey Haessler
Toomas Haller
Kathleen M. Harris
John Hokanson
JoukeJan Hottenga
Yi-Jen Hung
Chii-Min Hwu
William Iacono
Yon Ho Jee
Eric O. Johnson
Eric Jorgenson
Anne E. Justice
Yoichiro Kamatani
Robert C. Kaplan
Jaakko Kaprio
Charles Kooperberg
Tellervo Korhonen
Wen-Jane Lee
Penelope A. Lind
Sharon Lutz
Reedik Mägi
Ani Manichaikul
Nicholas G. Martin
Ravi Mathur
Nana Matoba
Patrick F. McArdle
Matt McGue
Matthew B. McQueen
Sarah E. Medland
Andres Metspalu
Braxton D. Mitchell
Matthew M. Moll
May E. Montasser
Kari E. North
Elizabeth C. Oelsner
Yukinori Okada
Nicholette D. Palmer
Teemu Palviainen
Ulrike Peters
Annette Peters
Tinca J.C. Polderman
Robert M. Reed
Alex P. Reiner
Stephen S. Rich
Nicole Richmond
Jerome I. Rotter
Nancy L. Saccone
Aladdin H. Shadyab
Nona Sotoodehnia
Moin Syed
Ruth Tal-Singer
Amy E. Taylor
Kent D. Taylor
Khanh K. Thai
John B. Whitfield
Gonneke Willemsen
Huichun Xu
Lisa R. Yanek
Jie Yin
Kristin L. Young
Kendra Young
Luisa Zuccolo
Chiara Batini
Andrew Bergen
Laura Bierut
Sean P. David
Sarah A. Gagliano Taliun
Dana B Hancock
Bibo Jiang
Marcus Munafò
Thorgeir Thorgeirsson
Dajiang J. Liu
Scott Vrieze
Journal name for most current submission
Nature
Associated TOPMed paper proposal
This manuscript has been approved by the original paper proposal's Working Group(s) or is "single PI" *
This manuscript has been approved by the original paper proposal's Working Group(s) or is "single PI"
Acknowledgments
I have followed instructions for TOPMed Acknowledgments
I've received approval for all data sets used in this manuscript, including adding new data sets and canceling all unused ones. *
I've received approval for all data sets used in this manuscript, including adding new data sets and canceling all unused ones.
I have followed the Data Use Limitations for each of the data sets used in this manuscript, if applicable. *
Yes
I've included at least 1 co-author from each study used in analysis or the PI declined an offer to have their study represented. *
Yes
I certify that all co-authors have reviewed and approved the manuscript for submission. *
Yes
I've included at least 1 DCC/ACC author, or they declined authorship or deemed acknowledgement sufficient.
I've included at least 1 DCC/ACC author, or they declined authorship or deemed acknowledgement sufficient.
I’ve included at least 1 IRC author, or they declined authorship or deemed acknowledgement sufficient.
I’ve included at least 1 IRC author, or they declined authorship or deemed acknowledgement sufficient.
I've included at least 1 author from relevant omics center(s) or they declined authorship or deemed acknowledgement sufficient.
I've included at least 1 author from relevant omics center(s) or they declined authorship or deemed acknowledgement sufficient.

TOPMed data used in this manuscript

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Parent Study: Consent Group Review Status Actions
AFLMU:HMB-IRB-PUB-COL-NPU-MDS Request cancelled by original requester
ARIC:DS-CVD-IRB Approved automatically after 2 weeks
ARIC:HMB-IRB Approved automatically after 2 weeks
Amish:HMB-IRB-MDS Approved automatically after 2 weeks
AustralianFamilialAF:HMB-NPU-MDS Request cancelled by original requester
BAGS:GRU-IRB Approved
BioMe:GRU Request cancelled by original requester
BioMe:HMB-NPU Request cancelled by original requester
BioVU_AF:HMB-GSO Request cancelled by original requester
Boston-Brazil_SCD:HMB-IRB-COL Request cancelled by original requester
CARDIA:HMB-IRB Request cancelled by original requester
CARDIA:HMB-IRB-NPU Request cancelled by original requester
CATHGEN:DS-CVD-IRB Request cancelled by original requester
CCAF:GRU-IRB Request cancelled by original requester
CFS:DS-HLBS-IRB-NPU Approved automatically after 2 weeks
CHS:DS-CVD-MDS Approved
CHS:DS-CVD-NPU-MDS Approved
CHS:HMB-MDS Approved
CHS:HMB-NPU-MDS Approved
COPDGene:DS-CS-RD Approved
COPDGene:HMB Approved
CRA:DS-ASTHMA-IRB-MDS-RD Approved
DECAF:GRU Request cancelled by original requester
DHS:DS-DHD-IRB-COL-NPU Approved automatically after 2 weeks
DHS:HMB-IRB-COL-NPU Approved automatically after 2 weeks
ECLIPSE:DS-CS-MDS-RD Approved
EGCUT:GRU Approved automatically after 2 weeks
EOCOPD:DS-CS-RD Approved
FHS:HMB-IRB-MDS Approved automatically after 2 weeks
FHS:HMB-IRB-NPU-MDS Approved automatically after 2 weeks
GALAII:DS-LD-IRB-COL Request cancelled by original requester
GENAF:HMB-NPU Request cancelled by original requester
GENOA:DS-ASC-RF-NPU Approved
GGAF:GRU Request cancelled by original requester
GOLDN:DS-CVD-IRB Approved
GenSalt:DS-HCR-IRB Approved automatically after 2 weeks
GenSalt:GRU-IRB Disapproved
GeneSTAR:DS-CVD-IRB-NPU-MDS Approved
HCHS_SOL:HMB Approved automatically after 2 weeks
HCHS_SOL:HMB-NPU Approved automatically after 2 weeks
HVH:DS-CVD-IRB-MDS Approved automatically after 2 weeks
HVH:HMB-IRB-MDS Approved automatically after 2 weeks
HyperGEN:DS-CVD-IRB-RD Approved
HyperGEN:GRU-IRB Approved automatically after 2 weeks
INSPIRE_AF:DS-MULTIPLE_DISEASES-MDS Request cancelled by original requester
IPF:DS-ILD-IRB-NPU Disapproved
IPF:DS-LD-IRB-NPU Approved
IPF:DS-PFIB-IRB-NPU Disapproved
IPF:DS-PUL-ILD-IRB-NPU Disapproved
IPF:HMB-IRB-NPU Approved
JHS:DS-FDO-IRB Approved
JHS:DS-FDO-IRB-NPU Approved
JHS:HMB-IRB Approved
JHS:HMB-IRB-NPU Approved
JHU_AF:HMB-NPU-MDS Request cancelled by original requester
LTRC:HMB-MDS Request cancelled by original requester
MESA:HMB Approved
MESA:HMB-NPU Approved
MGH_AF:DS-AF-IRB-RD Request cancelled by original requester
MGH_AF:HMB-IRB Request cancelled by original requester
MLOF:HMB-PUB Request cancelled by original requester
MPP:HMB-NPU-MDS Request cancelled by original requester
Mayo_VTE:GRU Approved automatically after 2 weeks
OMG_SCD:DS-SCD-IRB-PUB-COL-MDS-RD Approved
PMBB_AF:HMB-IRB-PUB Request cancelled by original requester
PUSH_SCD:DS-SCD-IRB-PUB-COL Request cancelled by original requester
Partners:HMB Request cancelled by original requester
PharmHU:DS-SCD Request cancelled by original requester
PharmHU:DS-SCD-RD Request cancelled by original requester
PharmHU:HMB Request cancelled by original requester
REDS-III_Brazil:GRU-IRB-PUB-COL-NPU Request cancelled by original requester
SAFS:DS-DHD-IRB-PUB-MDS-RD Approved
SAGE:DS-LD-IRB-COL Request cancelled by original requester
SARP:GRU Approved automatically after 2 weeks
Samoan:GRU-IRB-PUB-COL-NPU-GSO Request cancelled by original requester
Sarcoidosis:DS-SAR-IRB Request cancelled by original requester
THRV:DS-CVD-IRB-COL-NPU-RD Approved automatically after 2 weeks
TOPCHeF:GRU-IRB Request cancelled by original requester
VAFAR:HMB-IRB Request cancelled by original requester
VU_AF:GRU-IRB Request cancelled by original requester
WGHS:HMB Approved automatically after 2 weeks
WHI:HMB-IRB Approved
WHI:HMB-IRB-NPU Approved
miRhythm:GRU Request cancelled by original requester
walk_PHaSST:HMB-IRB-PUB-COL-NPU-MDS-GSO Request cancelled by original requester
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