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A genetic association study of circulating coagulation Factor VIII and von Willebrand Factor levels

Manuscript ID: 16379

Submitting Author
de Vries, Paul
Submitting Author's Email
Authors
Paul S. de Vries1,*, Paula Reventun2,*, Michael R. Brown1, Adam S. Heath1, Jennifer E. Huffman3, Ngoc-Quynh Le4, Allison Bebo1, Jennifer A. Brody5, Gerard Temprano-Sagrera4, Laura M. Raffield6, Ayse Bilge Ozel7, Florian Thibord8, Deepti Jain9, Joshua P. Lewis10, Benjmain A.T. Rodriguez8, Nathan Pankratz11, Kent D. Taylor12, Ozren Polasek13, Ming-Huei Chen8, Lisa R. Yanek2, German D. Carrasquilla14,15, Riccardo E. Marioni16, Marcus E. Kleber17,18, David-Alexandre Trégouët19, Jie Yao12, Ruifang Li-Gao20, Peter K. Joshi21, Stella Trompet22, Angel Martinez-Perez4, Mohsen Ghanbari23, Tom E. Howard24, Alex P. Reiner25, Marios Arvanitis2, Kathleen A. Ryan10, Traci M. Bartz26, Igor Rudan21, Nauder Faraday27, Allan Linneberg28,29, Lynette Ekunwe30, Gail Davies31, Graciela E. Delgado18, Pierre Suchon32,33, Xiuqing Guo12, Frits R. Rosendaal20, Lucija Klaric34, Raymond Noordam22, Frank van Rooij23, Joanne E. Curran24, Wheeler M. Marsha35, William O. Osburn2, Jeffrey R. O'Connell10, Eric Boerwinkle1,36, Andrew Beswick37, Bruce M. Psaty38,5, Ivana Kolcic13, Juan Carlos Souto39,4, Lewis C. Becker2, Torben Hansen14, Margaret F. Doyle40, Sarah E. Harris31, Angela P. Moissl41,42, Jean-François Deleuze43,44, Stephen S. Rich45, Astrid van Hylckama Vlieg20, Harry Campbell21, David J. Stott46, Jose Manuel Soria4, Moniek P.M. de Maat47, Laura Almasy48,49, Lawrence C. Brody50, Paul L. Auer51, Braxton D. Mitchell10,52, Yoav Ben-Shlomo53, Myriam Fornage54,1, Caroline Hayward34, Rasika A. Mathias2, Tuomas O. Kilpeläinen14, Leslie A. Lange55, Simon R. Cox31, Winfried März56,18, Pierre-Emmanuel Morange32,33, Jerome I. Rotter12, Dennis O. Mook-Kanamori20,57, James F. Wilson21, Pim van der Harst58, J. Wouter Jukema59,60, M. Arfan Ikram23, John Blangero24, Charles Kooperberg25, Karl C. Desch61, Andrew D. Johnson8, Maria Sabater-Lleal4,62,*, Charles J. Lowenstein2,*, Nicholas L. Smith63,64,65,*, and Alanna C. Morrison1,*
Journal name for most current submission
Blood
Associated TOPMed paper proposal
This manuscript has been approved by the original paper proposal's Working Group(s) or is "single PI" *
This manuscript has been approved by the original paper proposal's Working Group(s) or is "single PI"
Acknowledgments
I have followed instructions for TOPMed Acknowledgments
I've received approval for all data sets used in this manuscript, including adding new data sets and canceling all unused ones. *
I've received approval for all data sets used in this manuscript, including adding new data sets and canceling all unused ones.
I have followed the Data Use Limitations for each of the data sets used in this manuscript, if applicable. *
Yes
I've included at least 1 co-author from each study used in analysis or the PI declined an offer to have their study represented. *
Yes
I certify that all co-authors have reviewed and approved the manuscript for submission. *
Yes
I've included at least 1 DCC/ACC author, or they declined authorship or deemed acknowledgement sufficient.
I have not
I’ve included at least 1 IRC author, or they declined authorship or deemed acknowledgement sufficient.
I have not
I've included at least 1 author from relevant omics center(s) or they declined authorship or deemed acknowledgement sufficient.
I have not

TOPMed data used in this manuscript

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Parent Study: Consent Group Review Status Actions
ARIC:DS-CVD-IRB Approved automatically after 2 weeks
ARIC:HMB-IRB Approved automatically after 2 weeks
Amish:HMB-IRB-MDS Approved
CARDIA:HMB-IRB Approved automatically after 2 weeks
CARDIA:HMB-IRB-NPU Approved automatically after 2 weeks
CHS:HMB-NPU-MDS Approved
FHS:HMB-IRB-MDS Approved automatically after 2 weeks
FHS:HMB-IRB-NPU-MDS Approved automatically after 2 weeks
GeneSTAR:DS-CVD-IRB-NPU-MDS Approved
JHS:DS-FDO-IRB Approved automatically after 2 weeks
JHS:DS-FDO-IRB-NPU Approved automatically after 2 weeks
JHS:HMB-IRB Approved automatically after 2 weeks
JHS:HMB-IRB-NPU Approved automatically after 2 weeks
MESA:HMB Approved
MESA:HMB-NPU Approved
SAFS:DS-DHD-IRB-PUB-MDS-RD Approved
WHI:HMB-IRB Approved
WHI:HMB-IRB-NPU Approved
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